Abstract P18: In Vivo Evaluation Of The Retina And Optic Nerve After Whole Eye Transplantation Using Optical Coherence Tomography, Manganese-enhanced Magnetic Resonance Imaging And Electroretinography

نویسندگان

  • Chiaki Komatsu
  • Lin He
  • Yolandi van der Merwe
  • Maxine R. Miller
  • Katie A. Lucy
  • Huamin Tang
  • Ian Rosner
  • Yang Li
  • Michael Steketee
  • Gadi Wollstein
  • Mario G. Solari
  • Joel S. Schuman
  • Kevin C. Chen
  • Kia M. Washington
چکیده

1Department of Plastic Surgery,University of Pittsburgh, Pittsburgh, PA, 2Department of Bioengineering,University of Pittsburgh, Pittsburgh, PA, 3Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, 4Department of Ophthalmology, New York University School of Medicine, New York, NY, 5Neuroimaging Laboratory, University of Pittsburgh, Pittsburgh, PA, 6Veterans Administration Pittsburgh Healthcare System, Pittsburgh, PA

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT.

PURPOSE Excitotoxicity has been linked to the pathogenesis of ocular diseases and injuries and may involve early degeneration of both anterior and posterior visual pathways. However, their spatiotemporal relationships remain unclear. We hypothesized that the effects of excitotoxic retinal injury (ERI) on the visual system can be revealed in vivo by diffusion tensor magnetic resonance imagining ...

متن کامل

Clinical Applications of Optical Coherence Tomography in Ophthalmology

Assessment of the peripapillary nerve fiber layer and macular thickness can be determined in ophthalmology using optical coherence tomography (OCT). Decreased nerve fiber layer thickness and macular ganglion cell thickness in optic nerve ischemia have been correlated with visual field loss. OCT allows deep optic nerve head evaluation which helps understand pathophysiology of diseases.  Furtherm...

متن کامل

Magnetic resonance imaging of feline eye

The purpose of this study was to investigate magnetic resonance imaging (MRI) of the normal feline eyeand optic nerves using T1-weighted and T2-weighted images. A total of 6 healthy female domestic short haircats age 2-2.5 years and weighing 3.2 ± 0.4 kg were selected. Magnetic resonance imaging data werecollected using GEMSOW (Philips) at a magnetic field strength of 1.5 T. Dorsal, sagittal, a...

متن کامل

Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration Treatments.

PURPOSE Apply manganese-enhanced magnetic resonance imaging (MEMRI) to assess ion channel activity and structure of retinas from mice subject to light-induced retinal degeneration treated with prophylactic agents. METHODS Abca4(-/-)Rdh8(-/-) double knockout mice with and without prophylactic retinylamine (Ret-NH2) treatment were illuminated with strong light. Manganese-enhanced MRI was used t...

متن کامل

Evaluation of the retina and optic nerve in a rat model of chronic glaucoma using in vivo manganese-enhanced magnetic resonance imaging

Glaucoma is a neurodegenerative disease of the visual system. While elevated intraocular pressure is considered to be a major risk factor, the primary cause and pathogenesis of the disease are still unclear. This study aims to employ in vivo manganese-enhanced magnetic resonance imaging (MEMRI) to evaluate dynamically the Mn(2+) enhancements in the visual components following an induction of oc...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2017